Evolutionary Dynamics of 2009 Pandemic Influenza A Virus Subtype H1N1 in South Africa During 2009–2010

Evolutionary pattern of pandemic influenza (H1N1) 2009 virus in the late phases of the 2009 pandemic.

Influenza A( H1N1)v has spread rapidly in all parts of the globe in 2009 as a true pandemic, although fortunately a clinically mild one. The relevant evolutionary steps for the new virus to adapt to human populations occurred very early during the pandemic, before the end of April. Of the several resulting clades or clusters, clade 7 appeared later and proved more successful, substituting all o...

2009 H1N1 Influenza Virus Seroepidemiology

Evolutionary pattern of pandemic influenza (H1N1) 2009 virus in the late phases of the 2009 pandemic. ΠPLOS Currents Influenza

Influenza A(H1N1)v has spread rapidly in all parts of the globe in 2009 as a true pandemic, although fortunately a clinically mild one. The relevant evolutionary steps for the new virus to adapt to human populations occurred very early during the pandemic, before the end of April. Of the several resulting clades or clusters, clade 7 appeared later and proved more successful, substituting all ot...

Evolutionary dynamics of local pandemic H1N1/2009 influenza virus lineages revealed by whole-genome analysis.

Virus gene sequencing and phylogenetics can be used to study the epidemiological dynamics of rapidly evolving viruses. With complete genome data, it becomes possible to identify and trace individual transmission chains of viruses such as influenza virus during the course of an epidemic. Here we sequenced 153 pandemic influenza H1N1/09 virus genomes from United Kingdom isolates from the first (1...

Pandemic (H1N1) 2009 influenza.

On 11 June 2009, the World Health Organization declared the first human influenza pandemic since 1968–1969. The responsible virus, pandemic (H1N1) 2009 influenza, is a novel triple-reassortant influenza A virus, incorporating avian, swine and human influenza genes.1 The virus is resistant to the anti-influenza medications, amantadine and rimantadine, but is generally sensitive to the neuraminid...